2023
40. Hacking mechanical memory. Eyckmans J., Biophys J. 2023, doi:10.1016/j.bpj.2023.03.012 Request PDF
39. Fibroblast clearance of damaged tissue following laser ablation in engineered microtissues. Griebel M.E., Vasan A., Chen C.S., Eyckmans J., APL Bioengineering. 2023, (7)016112 Request PDF
2022
38. Mechanical response of cardiac microtissues to acute localized injury. Das S.L., Sutherland B.P., Eyckmans J., Chen C.S., Am J Physiol Heart Circ Physiol. 2022, 323(4):H738-H748 Request PDF
37. Engineering a living cardiac pump on a chip using high-precision fabrication. Michas C., Çagatay M.K., Nautiyal P., Seidman J.G., Seidman C.E., Agarwal A., Ekinci K., Eyckmans J., White A.E., Chen C.S., Sci Adv. 2022, 8(16)eabm3791 Request PDF
36. Notch1 and Notch3 coordinate for pnricyte-induced stabilization of vasculature. Tefft J.B., Bays J.L., Lammers A., Kim S., Eyckmans J., Chen C.S., Am J Physiol Cell Physiol. 2022 Request PDF
2021
35. Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization. Zhang K., Cloonan P.E., Sundaram S., Liu F., Das S.L., Ewoldt J.K., Bays J.L., Tomp S., Toepfer C.N., Marsiglia J.D.C., Gorham J., Reichart D., Eyckmans J., Seidman J.G., Seidman C.E., Chen C.S., Sci Adv. 2021, 7(42)eabh3995 Request PDF
34. Extracellular matrix alignment directs provisional matrix assembly and 3D fibrous tissue closure. Das, S.L., Bose P., Lejeune M., Reich D., Chen C.S., Eyckmans J., Tissue Eng. 2021, Request PDF
33. Force-FAK signaling coupling at individual focal adhesions coordinates mechanosensing and microtissue repair. Zhou D.W., Fernández-Yagüe M.A., Holland E.N., García A.F., Castro N.S., O’Neill E.B., Eyckmans J. Chen C.S., Fu J., Schlaepfer D.D., García A.J., Nat Comm. 2021, 12:2359 Request PDF
32. Reconstituting the dynamics of endothelial cells and fibroblasts in wound closure. Tefft J.B., Chen C.S., Eyckmans J., APL Bioeng. 2021, 016102 Request PDF
2020
31. Transient support from fibroblasts is sufficient to drive functional vascularization in engineered tissues. Song H-H., Lammers A., Sundaram S., Rubio L., Chen A.X., Li L., Eyckmans J., Bhatia S.N., Chen C.S., Adv. Func. Mater. 2020, 2003777 Request PDF
2019
30. A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling. Nguyen D-H. T., Lee E., Alimperti S., Norgard R.J., Wong A., LeeJ-K., Eyckmans J., Stanger B.Z., Chen C.S., Sci. Adv. 2019, Aug; 28;5(8) Request PDF
29. Surface and bulk stresses drive morphological changes in fibrous microtissues. Mailand E., Li B., Eyckmans J, Bouklas N., Sakar M.S., Biophys J., 2019, Sep;117(5):975-986 Request PDF
28. Myosin IIA-mediated forces regulate multicellular integrity during vascular sprouting. Yoon C.*, Choi C.*, Stapleton S.*, Mirabella T., Howes C., Dong L., King J., Yang J., Oberai A., Eyckmans J.*, Chen C.S.*, MBoC, 2019;30(16):1974-1984Request PDF
27. A BMP/activin A chimera is superior to native BMPs and induces bone repair in nonhuman primates when delivered in a composite matrix. Seeherman H.J., Berasi S.P., Brown C.T., Martinez R.X., Juo Z.S., Jelinsky S., Cain M.J., Grode J., Tumelty K.E., Bohner M., Grinberg O., Orr N., Shoseyov O., Eyckmans J., Chen. C.S., Morales P.R., Wilson C.G., Vanderploeg E.J., Wozney J.M., Sci Trans Med. 2019, Apr;11(489)Request PDF
26. Studies of 3D directed cell migration enabled by direct laser writing of curved wave topography. Cheng D., Jayne R.K., Tamborini A., Eyckmans J.*, White A.E.*, Chen C.S*., Biofabrication 2019, Feb; 11(2):021001Request PDF
2018
25. Effects of geometry on the mechanics and alignment of three dimensional engineered microtissues. Bose P., Eyckmans J., Nguyen T.D., Chen C.S., Reich D.H., ACS Biomaterials. 2019;5(8):3843-3855Request PDF
24. Fabrication and mechanical properties measurements of 3D microtissues for the study of cell-matrix interactions. Bose, P., Huang, C.Y., Eyckmans, J., Chen, C.S., and Reich, D.H., Methods in Molecular Biology: The Surfaceome: Methods and Protocols (2018), eds Boheler KR & Gundry RL (Springer).Request PDF
23. Force generation via b-cardiac myosin, titin, and a-actinin drives cardiac sarcomere assembly from cell-matrix adhesions. Chopra A.*, Kutys M.L.*, Zhang K*, Polacheck W.J., Sheng C.C., Luu R.J., Eyckmans J., Hinson J.T.*, Seidman J.G.*, Seidman C.E.*, Chen C.S.*, Dev Cell. 2018, Jan;44(1):87-96.Request PDF
2017
22. A non-canonical Notch complex regulates adherens junctions and vascular barrier function. Polacheck W.J.*, Kutys M.L.*, Yang J., Eyckmans J., Wu Y., Vasavada H., Hirschi K., Chen C.S., Nature 2017, Dec; 552(7684):258-262.Request PDF
21. Designer biomaterials for mechanobiology, Li L.Q., Eyckmans J.*, Chen C.S.*, Nat. Mat. 2017, Nov;16(12):1164-1168.Request PDF
20. Making bone via nanoscale kicks, Eyckmans J.* and Chen C.S.*, Nat Biomed Eng. 2017, Sept;1:689-690.Request PDF
19) Three-dimensional biomimetic vascular model reveals a RhoA, Rac1, and N-cadherin balance in mural cell-endothelial cell-regulated barrier function. Alimperti A.*, Mirabella T.*, Bajaj V., Polacheck W., Pirone D.M., Duffield J., Eyckmans J., Assoian R.K., and Chen C.S., Proc Natl Acad Sci USA. 2017 Aug;114(33):8758-8763. Request PDF
18. 3D Culture models of tissues under tension. Eyckmans J.*and Chen C.S.*, J Cell Sci. 2017, Jan; 130(1):63-70. Request PDF
2016
17. Cellular forces drive tissue-scale matrix assembly in fibrous tissue repair. Sakar M.*, Eyckmans J.*, Pieters R., Eberli D., Nelson B.J. and Chen C.S., Nat Comm. 2016 Mar;7:11036 Request PDF
2015
16. Patterning vascular networks in vivo for tissue engineering applications. Chaturvedi, R.R., Stevens K.R., Solorzano R.D., Schwartz R.E., Eyckmans J., Baranski J.D., Stapleton S., Bhatia S.N., and Chen C.S., Tissue Eng Part C. 2015 May;21(5):509-17Request PDF
2014
15. Stem cell differentiation: sticky mechanical memory. Eyckmans J., Chen C.S., Nat Mat. 2014 Jun;13(6):542-543.Request PDF
2013
14. Geometric control of vascular networks to enhance engineered tissue integration and function. Baranski J.*, Chaturvedi R.R.*, Stevens K.R.*, Eyckmans J., Carvahlo B., Solorzano R.D., Yang M.T., Miller J.S., Bhatia S.N., Chen C.S., Proc. Natl. Acad. Sci. U.S.A. 2013 May;110(19):7586-91. Request PDF
13. Targeted osteogenic differentiation in vitro leads to robust ectopic bone formation in vivo. Eyckmans J.*, Roberts S.J.*, Bolander J., Schrooten J., Chen C.S., Luyten F.P., , Biomaterials 2013 Jun;34(19):4612-21. Request PDF
2012
12. Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells. Eyckmans J.*, Lin L.G.*, Chen C.S., Biology Open. 2012 Nov 15;1(11):1058-1068. Request PDF
11. The effect of activating Fibroblast Growth Factor Receptor 3 mutations on human periosteal cell dynamics. Bolander J., Roberts S.J., Eyckmans J., Geris L., Luyten F.P., J Tissue Sci Eng. 2012 S2:003 doi:10.4172/2157-7552.S2-003Request PDF
10. BMP-2-Induced Signaling and Osteogenesis is Regulated by Cell Shape, RhoA/ROCK, and Cytoskeletal Tension. Wang Y-K., Yu X., Cohen D.M., Wozniak M.A., Yang M.T., Eyckmans J., Chen C.S., Stem Cells Dev. 2012 May 1;21(7):1176-86.Request PDF
2011
9. A hitchhiker’s guide to mechanobiology.Eyckmans J., Boudou T., Yu X., Chen C.S., Dev Cell. 2011 Jul 19;21(1):35-47.Request PDF
8. Does tranexamic acid stabilised fibrin support the osteogenic differentiation of human periosteum derived cells? Demol J., Eyckmans J., Roberts S.J., Luyten F.P., Van Oosterwyck H., Eur Cell Mater. 2011 Mar 22;21:272-85.Request PDF
7. Osteoconductive and bioresorbable composites based on poly(L,L-lactide) and pseudowollastonite: from synthesis and interfacial compatibilization to in vitro bioactivity and in vivo osseointegration studies. Raquez J.M., Barone D.T., Luklinska Z., Persenaire O., Belayew A., Eyckmans J., Schrooten J., Dubois P., Biomacromolecules. 2011 Mar 14;12(3):692-700. Request PDF
2010 and earlier
6. Effects of MRI Contrast Agents on the Stem Cell Phenotype. Crabbe A., Vandeputte C., Dresselaers T., Ayuso Sacido A., Manuel Garcia Verdugo J., Eyckmans J., Luyten F.P., Van Laere K., Verfaillie C.M., Himmelreich U. Cell Trans. 2010;19(8):919-36.Request PDF
5. A clinically relevant model for osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling. Eyckmans J., Roberts S.J., Schrooten J., Luyten F.P., J Cell Mol Med. 2010 Jun;14 (6B):1845-56 Request PDF
4. Bone augmentation with autologous periosteal cells and two different calcium phosphate scaffolds under an occlusive titanium membrane. Maréchal M., Eyckmans J., Schrooten J., Schepers E., Luyten F.P., van Steenberghe D., J. Periodontol. 2008 May;79(5):896-904 Request PDF
3. Species specificity of ectopic bone formation by periosteum-derived mesenchymal progenitor cells. Eyckmans J., Luyten F.P., Tissue Eng. 2006 Aug;12(8):2203-13. Request PDF
2. Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis. De Bari C., Dell’Accio F., Vanlauwe J., Eyckmans J., Khan I.M., Archer C.W., Jones E.A., McGonagle D., Mitsiadis T.A., Pitzalis C., and Luyten F.P. Arthritis Rheum. 2006 Apr;54, 1209-1221. Request PDF
1. Efficient lentiviral transduction and improved engraftment of human bone marrow mesenchymal cells. Van Damme A., Thorrez L., Ma L., Vandenburgh H., Eyckmans J., Dell’accio F., De Bari C., Luyten F., Lillicrap D., Collen D., Vandendriessche T., and Chuah M.K. Stem Cells. 2006 Apr; 24(4):896-907 Request PDF
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