The Eyckmans Lab is driven by a central mission: to uncover the mechanisms behind tissue regeneration, impaired wound healing, and fibrosis in order to develop transformative therapies that improve patient outcomes. Our approach integrates cutting-edge expertise from medicine, mechanobiology, synthetic biology, and biomaterials. We focus on the interactions between cells and the extracellular matrix (ECM) and how mechanical forces influence healing—whether tissues regenerate, form scars (fibrosis), or struggle to heal. We’re investigating how cells build ECM into working tissues and how the ECM can guide cells to promote better healing. By creating innovative biomimetic models of tissue repair and utilizing advanced genetic and protein engineering to manipulate the ECM, we aim to push the boundaries of regenerative medicine. If you want to learn more about our research, click on the research tab!